US Vice-President-elect Mike Pence was booed on Friday at a performance of the hit musical Hamilton.
After the show, a cast member thanked Mr Pence for attending and read a letter to him on stage.
“We, sir, are the diverse America who are alarmed and anxious that your new administration will not protect us,” Brandon Dixon said.
The message was reportedly penned by the show’s writers when they learned that Mr Pence planned to attend.
Dixon’s reading was greeted with cheers from the audience at the Richard Rogers Theatre in New York.
An audience member tweeted to say there was a three-minute standing ovation when one character performed a song directly to Mr Pence which included the lyrics: “A small query for you / What comes next? / You’ve been freed / Do you know how hard it is to lead?”
Mr Pence was loudly booed as he entered the theatre, and audience members said the performance was repeatedly stopped because of jeers.
When Mr Dixon addressed theatregoers at the end, he urged them not to boo and asked Mr Pence, who was leaving, to stay and listen.
“You know, we had a guest in the audience this evening, and Vice-President-elect Pence, I see you are walking out but I hope you will hear us.
“There’s nothing to boo here, ladies and gentlemen… We have a message for you, sir, and we hope you will hear us out.”
Mr Dixon continued: “We truly hope that his show has inspired you to uphold our American values and work on behalf of all of us.
“We truly thank you for sharing this wonderful American story told by a diverse group of men and women of different colours, creeds, and orientations.”
On Saturday, Kellyanne Conway, campaign manager for President-elect Donald Trump and a key member of his transition team, tweeted that Mr Pence deserved more respect.
A staunch conservative, Mr Pence sparked an outcry earlier this year after signing a law critics said discriminated against the LGBT community by allowing businesses to refuse service over religious beliefs. He later amended the bill.
He is not the first high-profile politician to attend the critically-acclaimed and hugely popular Hamilton, which tells the story of US founding father Alexander Hamilton.
President Barack Obama saw the musical last year and joined the cast backstage after the performance.
Hillary Clinton, who lost to Mr Trump in last week’s election, also saw the show. She was supported by its creator, Lin-Manuel Miranda, during her campaign.